Qualifications
Education: Associate/BS/BA/Master's with minimum of 1 year of industry or academia experience. Strong knowledge in immunohistochemistry and in situ hybridization including method development, optimization, and troubleshooting.
Must have:
• Processing and embedding formalin-fixed paraffin embedded (FFPE) tissues
• Sectioning FFPE and frozen blocks.
• Performing histology-based experiments such as IHC, IF, or RNAscope (manually or with autostainers).
• Interest and/or understanding of oncology, immune-oncology, and / or immunology.
Nice to haves:
• Performing image analysis using open source and/or commercially available software.
• Experience in image acquisition and basic microscopy skills.
• Strong data analysis skills including a practical knowledge of statistics
• Experience working with LIMS system
• Experience working with multiplex staining histology platforms (eg Phenocycler, COMET, etc)
Preferred Qualifications:
• Experience with automated immunostainers (e.g. Leica Bond).
• Experience with whole slide imaging.
• Tissue processing & embedding, microtome and cryostat sectioning.
Responsibilities
The In Vivo Pharmacology group within the Quantitative Biosciences Department is seeking a motivated and technically skilled scientist with immunohistochemistry expertise in oncology, immune-oncology, and / or immunology to join our Boston-based Exploratory Discovery team. Candidates will be able to work independently, but will also be expected to proactively collaborate with colleagues across disciplines. Primary responsibilities include design and execution of immunohistochemistry (IHC) and histology experiments of human and mouse tissues to support the preclinical and clinical development of Client targets and drugs developed by ***. The candidate will be an active participant in the positive and critical scientific dialogue that is necessary to progress our programs.
The responsibilities of the position include:
• Optimize, validate, and execute IHC assays using appropriate controls
• Build and manage a library of archival FFPE specimens
• Contribute to the characterization and validation of compound and/or antibody activity using biomarker histology.
• Communicate data clearly and concisely to the appropriate teams and stakeholders.
• Be able to thrive in a team environment.
Nesco Resource offers a comprehensive benefits package for our associates, which includes a MEC (Minimum Essential Coverage) plan that encompasses Medical, Vision, Dental, 401K, and EAP (Employee Assistance Program) services.
Nesco Resource provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state, or local laws.
