Come join the Cardiometabolic Research (CMR) team at ***! We are focused on the discovery and early phase clinical development of biologic, small molecule, oligonucleotide, and cell therapies for treatment of diabetes, obesity, cardiovascular disease, and associated metabolic disorders. The Data Science team within CMR is seeking someone with wide-ranging experience in next-generation sequencing library preparation to help achieve our research goals. The successful candidate will be responsible for RNA-seq, scRNA-seq, snRNA-seq, and other types of -seq library preparations for all CMR groups. This will be a cross-therapeutic area role encompassing opportunities to impact science in the Boston team.
Job Requirements
• B.S. and/or M.S. in biological or biochemical sciences (or a related field) with 3-5 years of laboratory research experience.
• Molecular biology mastery of nucleic acid extraction and purification, quantification, NGS library preparation/QC, and qPCR.
• Strong background in NGS technologies and their applications, including quantification, sequencing, and data QC (preferably Illumina). Direct experience with RNA-seq (bulk) and amplicon-seq.
• Direct experience with single-cell and single-nucleus RNA-seq library preparation is required. Candidates must be familiar with multiple scRNA-seq/snRNA-seq platforms (e.g., 10X Genomics Chromium, Illumina PIP-seq, ScaleBio, or Parse Biosciences).
Additional Skills/Preferences:
• Familiarity with CRISPR-based gene editing and high-throughput screening is a plus.
• Experience with automation is a plus (Mantis, Integra systems, Liquid Handlers, SPTLabtech Firefly, Tecan, etc).
• Strong organizational, time management, and communication skills.
• Experience with documentation in electronic notebook software.
Nesco Resource offers a comprehensive benefits package for our associates, which includes a MEC (Minimum Essential Coverage) plan that encompasses Medical, Vision, Dental, 401K, and EAP (Employee Assistance Program) services.
Nesco Resource provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state, or local laws.
